American Airlines operates from Barcelona–El Prat Airport, serving passengers traveling to and from Barcelona. The American Airlines Barcelona terminal is located at Terminal 1 (T1), which handles most international and long-haul flights at the airport.

The American Airlines Barcelona terminal is known for its modern infrastructure and passenger-friendly layout. Travelers can access a variety of amenities, including duty-free shops, restaurants, cafes, and comfortable waiting areas. The terminal is designed to ensure smooth navigation, making it easy for passengers to move through check-in, security, and boarding processes.